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DPSL

Humanities

From Molecular Genetics to Genomics -The Mapping Cultures of Twentieth-Century Genetics

Editor : Hans-Jörg Rheinberger, Jean-Paul Gaudillière

Illustrations : 27 line drawings and 20 b+w photos

Master eBook ISBN10 : 0-203-37533-5

Master eBook ISBN13 : 978-0-203-37533-4

No of pages : 240

eBook Price : $228

Originally Published : 7 Oct 2004

With the rise of genomics, the life sciences have entered a new era. Maps of genomes have become the icons for a comprehensive knowledge of the organism on a previously unattained level of complexity. This book provides an in-depth history of molecular genetics and genomics.
The first section of the book shows how the cartography of classical genetics was linked to the molecular analysis of gene structure through the introduction of new model organisms, such as bacteria, and through the invention of new experimental tools, such as gene transfer. The second section addresses the development of human genome sequencing in all its technical, epistemic, social, and economic complexity.
With its detailed analyses of the scientific practices and its illustration of the diversity of mapping, this book is a significant contribution to the history of genetics.
A companion volume from the same editors - Classical Genetic Research and Its Legacy: The mapping cultures of twentieth century genetics - covers the history of mapping procedures as they were developed in classical genetics.



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Table of contents : Section 1. Molecularizing Maps
1. Angela Creager. Mapping Genes in Microorganisms
2. Frederic L. Holmes. Seymour Benzer and the Convergence of Molecular Biology with Classical Genetics
3. Marcel Weber. Walking on the Chromosome: Drosophila and the Molecularization of Development
4. Scott Gilbert. Gene Expression Maps: The Cartography of Transcription
5. Soraya de Chadarevian. Mapping the Worm's Genome: Tools, Networks, Patronage
Section 2. The Moral and the Political Economy of Human Genome Sequencing
6. Stephen Hilgartner. Making Maps and Making Social Order: Governing American Genome Centers, 1988-93
7. Alain Kaufmann. Mapping the Human Genome at Généthon Laboratory: The French Muscular Dystrophy Association and the Politics of the Gene
8. Adam Bostanci. Sequencing Human Genomes
9. Gísli Pálsson. Decoding Relations and Disease: The Icelandic Biogenetic Project


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